PBIT
Product Specifications
CAS Number
2514-30-9
Target
Histone Demethylase
Applications
Epigenetics
Molecular Formula
C14H11NOS
Additionnal Information
PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. It inhibits JARID1B (KDM5B/PLU1), JARID1Aand JARID1C with an IC50 of 3 μM, 6 μM and 4.9 μM respectively. It is capable of inhibiting the multiplication of breast cancer cell lines expressing high levels of JARIDB1.
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