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9-cis-Retinoic acid

Product Specifications

CAS Number

5300-03-8

Synonyms

Alitretinoin, ALRT 1057

Target

Retinoid Receptor

Applications

Metabolism

Molecular Formula

C20H28O2

Additionnal Information

9-cis-Retinoic acid (Alitretinoin, ALRT 1057) is an active metabolite of vitamin A that functions as a high-affinity ligand for retinoid X receptors (RXRs) and also activates retinoic acid receptors (RARs) . It inhibits adipogenesis by activating RXR while simultaneously decreasing RXRα and PPARγ levels in an RXR activation-independent manner.

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