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PRT543

Product Specifications

CAS Number

1989620-03-2

Target

PRMT

Applications

Epigenetics

Molecular Formula

C17H17ClN4O4

Additionnal Information

PRT543 is a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) with broad antitumor activity in vitro and in vivo. It also inhibits the methyltransferase activity of the PRMT5/MEP50 complex with an IC50 of 10.8 nM.

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