Gamcemetinib (CC-99677)
Product Specifications
CAS Number
1887069-10-4
Synonyms
BMS-986371
Target
MAPKAPK2
Applications
MAPK
Molecular Formula
C22H20ClN5O3S
Additionnal Information
Gamcemetinib (CC-99677, BMS-986371) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) (MAPKAPK2 (MK2) ) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM) .
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