What is the catalog number for KT 474?

The catalog number for KT 474 is E1655-1mg.

What sizes are available for KT 474?

KT 474 is available in the following size(s): 1 mg.

KT 474 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures KT 474?

KT 474 is manufactured by Bimake.

What is the estimated delivery time for KT 474?

Estimated delivery time for KT 474 is approximately 15 business day(s), depending on your location.

KT 474

Product Specifications

CAS Number

2432994-31-3

Synonyms

SAR-444656

Target

IRAK

Applications

Immunology & Inflammation

Molecular Formula

C44H49F2N11O6

Additionnal Information

KT-474 (SAR444656) is a selective small-molecule degrader of IRAK4 in development for the treatment of TLR/IL-1R–driven autoimmune diseases. KT-474 potently downregulates R848 (TLR7/8) and lipopolysaccharide (LPS) -induced IL-6 and IL-8 production in peripheral blood mononuclear cells (PBMCs) .