What is the catalog number for Exarafenib?

The catalog number for Exarafenib is E1649-5mg.

What sizes are available for Exarafenib?

Exarafenib is available in the following size(s): 5 mg.

Is Exarafenib in stock?

Exarafenib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Exarafenib?

Exarafenib is manufactured by Bimake.

What is the estimated delivery time for Exarafenib?

Estimated delivery time for Exarafenib is approximately 15 business day(s), depending on your location.

Exarafenib

Product Specifications

CAS Number

2639957-39-2

Synonyms

KIN-002787, KIN-2787, RAF/KIN_2787

Target

Raf

Applications

MAPK

Molecular Formula

C26H34F3N5O3

Additionnal Information

Exarafenib (KIN-002787, KIN-2787, RAF/KIN_2787) is an orally-available, selective inhibitor of pan-RAF. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. KIN-2787 exhibits low nanomolar to picomolar potency against RAF1, BRAF, and ARAF with an IC50 of 0.06-3.46 nM with minimal activity towards non-RAF kinases.