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RK-701

Product Specifications

CAS Number

2648855-18-7

Target

G9a/GLP

Applications

Epigenetics

Molecular Formula

C26H30N4O3

Additionnal Information

RK-701 is a highly selective, potent, and low-toxicity inhibitor of histone methyltransferases G9a and GLP1 with IC50 values of 23-27 nM and 53 nM. RK-701 treatment induces fetal globin expression in human erythroid cells and in mice and plays an essential role in γ-globin induction. RK-701 is used in the research of sickle cell disease.
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