Vevorisertib trihydrochloride
Product Specifications
CAS Number
1416775-08-0
Synonyms
ARQ 751 trihydrochloride
Target
Akt
Applications
PI3K/Akt/mTOR
Molecular Formula
C35H38N8O.3ClH
Additionnal Information
Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is a selective, allosteric inhibitor of pan-AKT and AKT1-E17K mutant with Kd values of 1.2 nM and 8.6 nM, respectively. It also has IC50 values of 0.55, 0.81, and 1.3 nM for AKT1, AKT2, and AKT3, respectively and can be used for the research of cancer.
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