AMG-193
Product Specifications
CAS Number
2790567-82-5
Target
PRMT
Applications
Epigenetics
Molecular Formula
C22H19F3N4O3
Additionnal Information
AMG-193 is an orally active and MTA-cooperative inhibitor of PRMT5 with potent biochemical and cellular activity. AMG-193, in combination with MTA, selectively targets and inhibits the growth of MTAP-deficient tumor cells by suppressing PRMT5, with an IC50 of 0.107 μM, while sparing normal cells that possess wild-type MTAP. AMG-193 also exhibits antitumor activity.
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Human IL-12A Protein (Arg 23-Ser 219) [Fc]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NBP1-72934 100 µg
Donkey Polyclonal Donkey anti-Mouse IgG (H+L) Secondary Antibody [DyLight 649] (Pre-absorbed)
Sign In for Pricing
View Details E3440-12-Biotin 100 µL
Epstein Barr Virus, Latent Membrane Protein 2A (EBV LMP2A, Human Herpes virus 4, HHV4, Latent Membrane Protein 2, LMP2, Terminal Protein) (Biotin) discontinued
Sign In for Pricing
View Details MBS8112118-01 0.1 mL
Anti-Thimet Oligopeptidase/THOP1 Antibody, Rabbit Polyclonal
Sign In for Pricing
View Details 
MBS8112118-02 5x 0.1 mL
Anti-Thimet Oligopeptidase/THOP1 Antibody, Rabbit Polyclonal
Sign In for Pricing
View Details