Edralbrutinib
Product Specifications
CAS Number
1858206-58-2
Synonyms
TG-1701
Target
BTK
Applications
Protein Tyrosine Kinase
Molecular Formula
C26H21F2N5O3
Additionnal Information
Edralbrutinib (TG-1701) is an irreversible, highly specific, and potent inhibitor of Bruton's tyrosine kinase (BTK) . TG-1701 shows similar efficacy but greater selectivity compared to the first-in-class BTK inhibitor ibrutinib, with a Kd value of 3 nmol/L, in both in vitro and in vivo models of B-cell non-Hodgkin lymphoma (B-NHL) .
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