What is the catalog number for LUNA18?

The catalog number for LUNA18 is E1576-1mg.

What sizes are available for LUNA18?

LUNA18 is available in the following size(s): 1 mg.

LUNA18 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LUNA18?

LUNA18 is manufactured by Bimake.

What is the estimated delivery time for LUNA18?

Estimated delivery time for LUNA18 is approximately 15 business day(s), depending on your location.

LUNA18

Product Specifications

CAS Number

2676177-63-0

Synonyms

Paluratide

Target

Ras

Applications

Apoptosis

Molecular Formula

C73H105F5N12O12

Additionnal Information

LUNA18 (Paluratide) is an orally bioavailable 11-mer cyclic peptide KRAS inhibitor for the intracellular tough target RAS. It binds to KRASG12D with a kd of 0.043 nM and blocks KRASG12D–SOS1 interaction at IC50 of < 2.2 nM. It also exhibits antiproliferative activity in KRAS-mutant cancer cell lines with an IC50 of 1.4 nM in AsPC-1 pancreatic cancer cells.