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NSC 663284

Product Specifications

CAS Number

383907-43-5

Synonyms

DA-3003-10

Target

CDK

Applications

Cell Cycle

Molecular Formula

C15H16ClN3O3

Additionnal Information

NSC 663284 (DA-3003-10) is a potent, cell-permeable, and irreversible dual specificity phosphatase inhibitor of Cdc25, and exhibits an IC50 of 0.21 μM for Cdc25B2 and is 20 and 450-fold highly selective against Cdc25B2. NSC 663284 also inhibits NSD2 with an IC50 of 170 nM via a direct interaction with the catalytic SET domain.
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