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M3541

Product Specifications

CAS Number

1360628-91-6

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Molecular Formula

C23H17FN6O2

Additionnal Information

M3541 is a potent and selective inhibitor of ATM kinase activity with an IC50 value of 0.25 nM in cell-free assays. M3541 suppresses double-strand breaks (DSB) repair, clonogenic cancer cell growth and potentiates antitumor activity of ionizing radiation in cancer cell lines.

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