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Sonrotoclax

Product Specifications

CAS Number

2383086-06-2

Synonyms

BGB-11417

Target

Bcl-2

Applications

Apoptosis

Molecular Formula

C49H59N7O7S

Additionnal Information

Sonrotoclax (BGB-11417) is a highly potent, orally active and selective inhibitor of Bcl2. Sonrotoclax demonstrates increased potency along with in vitro and in vivo inhibitory activity against both WT Bcl-2 and the G101V mutant. Bcl-xL Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines.

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