Sonrotoclax
Product Specifications
CAS Number
2383086-06-2
Synonyms
BGB-11417
Target
Bcl-2
Applications
Apoptosis
Molecular Formula
C49H59N7O7S
Additionnal Information
Sonrotoclax (BGB-11417) is a highly potent, orally active and selective inhibitor of Bcl2. Sonrotoclax demonstrates increased potency along with in vitro and in vivo inhibitory activity against both WT Bcl-2 and the G101V mutant. Bcl-xL Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines.
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