Zamaporvint (RXC004)
Product Specifications
CAS Number
1900754-56-4
Target
Wnt/beta-catenin
Applications
Cytoskeletal Signaling
Molecular Formula
C21H16F3N7O
Additionnal Information
Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. It targets membrane-bound o-acyltransferase Porcupine and inhibits Wnt ligand palmitoylation, secretion, and pathway activation. RXC004 exhibits potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines and possesses multiple antitumor mechanisms.
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