Tinengotinib
Product Specifications
CAS Number
2230490-29-4
Synonyms
TT-00420
Target
Aurora Kinase
Applications
Cell Cycle
Molecular Formula
C20H19ClN6O
Additionnal Information
Tinengotinib (TT-00420) is a novel multiple kinase inhibitor that strongly inhibits Aurora A/B with IC50 values of 1.2/3.3 nM respectively. It also exhibits potent inhibitory activity on FGFR1/2/3, VEGFR1, JAK1/2, and CSF1R and can be used to treat several prominent signaling pathways in triple-negative breast cancer (TNBC) .
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