Nesuparib
Product Specifications
CAS Number
2055357-64-5
Synonyms
JPI-547, NOV140201
Target
PARP
Applications
DNA Damage/DNA Repair
Molecular Formula
C23H24N6O
Additionnal Information
Nesuparib (JPI-547, NOV140201) is a potential inhibitor of both PARP and tankyrases, with IC50 of 0.005 μM, 0.001 μM, 0.002 μM, and ND for TNKS1, TNKS2, PARP1, and PARP2, respectively. Nesuparib exhibits anti-tumor activity in BRCA-deficient xenograft models.
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