Butyrolactone 3
Product Specifications
CAS Number
778649-18-6
Synonyms
MB-3
Target
Histone Acetyltransferase
Applications
Epigenetics
Molecular Formula
C9H12O4
Additionnal Information
Butyrolactone 3 is a non-irreversible inhibitor of the histone acetyltransferase Gcn5, with an IC50 of 100 μM. It selectively targets the Gcn5/PCAF family exhibiting weak inhibition of CBP HAT with an IC50 of 0.5 mM and also inhibits pre-mRNA splicing in vitro before catalysis, with an IC50 of 0.5 mM.
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