KP-457
Product Specifications
CAS Number
1365803-52-6
Synonyms
TNF‐α‐converting enzyme
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Molecular Formula
C21H24N2O7S2
Additionnal Information
KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17 with IC50 of 11.1 nM/L (cell-free assay) . It also cleaves various molecules such as GPIbα, GPV, and TNF-α.
Storage Conditions
3 years -20°C powder
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