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MS177

Product Specifications

CAS Number

2225938-86-1

Target

Histone Methyltransferase

Applications

Epigenetics

Molecular Formula

C48H55N11O8

Additionnal Information

MS177 is an EZH2-targeting PRTOAC degrader and a potent inhibitor of enzymatic EZH2, that effectively depletes both canonical EZH2–PRC2 and noncanonical EZH2–cMyc complexes. MS177 induces leukemia cell growth inhibition, apoptosis, and cell cycle progression arrest.

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