CHD1Li 6.11
Product Specifications
CAS Number
2716890-91-2
Smiles
CC1=CC (=NC (=N1) N2CCCC2) NC3=CC=C (NC (=O) CC4=CC (=CS4) Br) C=C3
Molecular Formula
C21H22BrN5OS
Additionnal Information
CHD1Li 6.11, a potent oncogenic chromodomain helicase DNA binding protein 1 like (CHD1L) inhibitor and an orally bioavailable antitumor agent, shows the enzymatic inhibition of the catalytic CHD1L (cat-CHD1L) recombinant protein with IC50 of 3.3 μM, and significantly reduces the tumor volume of colorectal cancer (CRC) xenografts generated from isolated quasi mesenchymal cells (M-Phenotype) .
Storage Conditions
3 years -20°C powder
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