GA-017
Product Specifications
CAS Number
2351906-74-4
Target
LATS
Applications
Hippo
Smiles
CC\C (=N\NC (=O) NCC1=CC (=CC=C1) O) C2=C (O) C (=C (O) C=C2) C
Molecular Formula
C18H21N3O4
Additionnal Information
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10±0.79 and 3.92±0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58±0.11 and 0.25±0.03 nM, respectively.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
133379-ML550 100 µL
SKIL (Ski-like Protein, Ski-related Oncogene, Ski-related Protein, SNO) (MaxLight 550)
Sign In for Pricing
View Details 033068-HRP 200 µL
C9, ID (C9, Complement component C9, Complement component C9a, Complement component C9b) (Azide free) (HRP)
Sign In for Pricing
View Details 
K1893-09A-Biotin 100 µL
KLRC1 (Killer Cell Lectin-like Receptor Subfamily C Member 1, CD159 Antigen-like Family Member A, CD159a, NK Cell Receptor A, NKG2A, NKG2, NKG2-A/B-activating NK Receptor, NKG2-A/NKG2-B Type II Integral Membrane Protein) (Biotin)
Sign In for Pricing
View Details