AACOCF3
Product Specifications
CAS Number
149301-79-1
Synonyms
Arachidonyl trifluoromethyl keton
Target
Phospholipase (e.g. PLA)
Applications
Metabolism
Molecular Formula
C21H31F3O
Additionnal Information
AACOCF3 (Arachidonyl trifluoromethyl ketone) is an inhibitor of cytosolic phospholipase A2 (cPLA2) and calcium-independent phospholipase A2 (iPLA2) with IC50 of 1.5 μM and 6.0 μM, respectively. It inhibits aortic osteoinductive signalling and vascular calcification in the cholecalciferol-overload mouse model.
Storage Conditions
2 years -20°C liquid
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