TRULI
Product Specifications
CAS Number
1424635-83-5
Target
LATS
Applications
Hippo
Smiles
O=C (N=C1SC=CN1CC2=CC=CC=C2) C3=C[NH]C4=NC=CC=C34
Molecular Formula
C18H14N4OS
Additionnal Information
TRULI inhibits both Lats1 and Lats2 with a IC50 of 0.2 nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear.
Storage Conditions
3 years -20°C powder
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