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TRULI

Product Specifications

CAS Number

1424635-83-5

Target

LATS

Applications

Hippo

Smiles

O=C (N=C1SC=CN1CC2=CC=CC=C2) C3=C[NH]C4=NC=CC=C34

Molecular Formula

C18H14N4OS

Additionnal Information

TRULI inhibits both Lats1 and Lats2 with a IC50 of 0.2 nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear.

Storage Conditions

3 years -20°C powder

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