What is the catalog number for JR14a?

The catalog number for JR14a is E1048-1g.

What sizes are available for JR14a?

JR14a is available in the following size(s): 1 g.

JR14a is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures JR14a?

JR14a is manufactured by Bimake.

What is the estimated delivery time for JR14a?

Estimated delivery time for JR14a is approximately 15 business day(s), depending on your location.

JR14a

Product Specifications

CAS Number

2411440-41-8

Target

Complement System

Applications

Immunology & Inflammation

Smiles

CC1=C (SC (=C1) C (C2=CC=C (Cl) C=C2) C3=CC=C (Cl) C=C3) C (=O) NC (CCCNC (N) =N) C (O) =O

Molecular Formula

C25H26Cl2N4O3S

Additionnal Information

JR14a, a selective and potent human Complement C3a receptor antagonist, which is assessed by inhibition of intracellular calcium release (IC50=10 nM) induced in human monocyte-derived macrophages by C3a, inhibition of β-hexosaminidase secretion (IC50=8 nM) from human LAD2 mast cells degranulated by C3a, and selectivity for human C3aR over C5aR.