GW280264X
Product Specifications
CAS Number
866924-39-2
Molecular Formula
C28H41N5O6S
Additionnal Information
GW280264X is a potent hydroxamate inhibitor of mixed ADAM10/TACE (ADAM17) . It potently blocks TACE (ADAM17) and ADAM10 with IC50s of 8.0 nM and 11.5 nM, respectively. It inhibits constitutive and PMA-inducible CX3CL1 shedding and increases adhesive properties in CX3CL1 transfected cells. Its treatment significantly improves functional recovery after spinal cord injury.
More Discoveries
Explore Other Products
Browse additional items from our catalog
