Masitinib mesylate
Product Specifications
CAS Number
1048007-93-7
Synonyms
AB-1010 mesylate
Target
C-Kit
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) CC2=CC=C (C=C2) C (=O) NC3=CC=C (C) C (=C3) NC4=NC (=CS4) C5=CN=CC=C5.C[S] (O) (=O) =O
Molecular Formula
C28H30N6OS.CH4O3S
Additionnal Information
Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit with IC50 of 200 nM for human recombinant c-Kit, also inhibits PDGFRα/β with IC50s of 540/800 nM, Lyn with IC50 of 510 nM for LynB, and, to a lesser extent, FGFR3 and FAK.
Storage Conditions
3 years -20°C powder
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