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COH-SR4

Product Specifications

CAS Number

73439-19-7

Target

AMPK

Applications

PI3K/Akt/mTOR

Smiles

ClC1=CC (=CC (=C1) NC (=O) NC2=CC (=CC (=C2) Cl) Cl) Cl

Molecular Formula

C13H8Cl4N2O

Additionnal Information

COH-SR4 suppresses adipogenesis in 3T3-L1 cells through indirect activation of AMPK and downstream modulation of the Mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, which blocks important regulators involved in protein synthesis, cell cycle progression, and expression of key transcription factors and their target adipogenic genes involved in lipid synthesis.

Storage Conditions

3 years -20°C powder

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