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MID-1

Product Specifications

CAS Number

312608-54-1

Target

IGF-1R

Applications

Protein Tyrosine Kinase

Smiles

CCOC1=CC=C (C=C1) C (=O) NC2=NC=C (S2) [N+] ([O-]) =O

Molecular Formula

C12H11N3O4S

Additionnal Information

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction, which can disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.

Storage Conditions

3 years -20°C powder

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