ALLO-2
Product Specifications
CAS Number
1357350-60-7
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
FC (F) (F) OC1=CC=C (C=C1) C2=NC (=NC=C2) NC3=CC4=C ([NH]N=C4) C=C3
Molecular Formula
C18H12F3N5O
Additionnal Information
ALLO-2 is a potent antagonist of both wild-type mouse Smo and drug-resistant D473H mutant human Smo that inhibits Smo agonist inhibited Gli-Luc activity in TM3-Gli-Luc cells with IC50 of 6 nM.
Storage Conditions
3 years -20°C powder
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