Esaxerenone (CS-3150)
Product Specifications
CAS Number
1632006-28-0
Target
Mineralocorticoid Receptor
Applications
Endocrinology & Hormones
Smiles
CC1=C ([N] (CCO) C=C1C (=O) NC2=CC=C (C=C2) [S] (C) (=O) =O) C3=CC=CC=C3C (F) (F) F
Molecular Formula
C22H21F3N2O4S
Additionnal Information
Esaxerenone (CS-3150), a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, binds to mineralocorticoid receptor and inhibits (3) H-aldosterone binding to mineralocorticoid receptor with an IC50 value of 9.4 nM. Esaxerenone (CS-3150) also has the property of increasing the likelihood of albuminuria returning to normal levels and reducing progression of albuminuria to higher levels.
Storage Conditions
3 years -20°C powder
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