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CNQX

Product Specifications

CAS Number

115066-14-3

Synonyms

6-cyano-7-nitroquinoxaline-2,3-dione

Target

GluR

Applications

Neuronal Signaling

Smiles

[O-][N+] (=O) C1=CC2=C (NC (=O) C (=O) N2) C=C1C#N

Molecular Formula

C9H4N4O4

Additionnal Information

CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) is an AMPA and kainate receptor antagonist with IC50 values are 0.3 μM and 1.5 μM for AMPA and kainate receptors, respectively. CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM) . CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons.

Storage Conditions

3 years -20°C powder

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