CNQX
Product Specifications
CAS Number
115066-14-3
Synonyms
6-cyano-7-nitroquinoxaline-2,3-dione
Target
GluR
Applications
Neuronal Signaling
Smiles
[O-][N+] (=O) C1=CC2=C (NC (=O) C (=O) N2) C=C1C#N
Molecular Formula
C9H4N4O4
Additionnal Information
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) is an AMPA and kainate receptor antagonist with IC50 values are 0.3 μM and 1.5 μM for AMPA and kainate receptors, respectively. CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM) . CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons.
Storage Conditions
3 years -20°C powder
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