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MRT-81

Product Specifications

CAS Number

1263132-08-6

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

COC1=C (OC) C (=CC (=C1) C (=O) NC (=S) NC2=CC=C (C) C (=C2) NC (=O) C3=CC=C (C=C3) C4=CC=CC=C4) OC

Molecular Formula

C31H29N3O5S

Additionnal Information

MRT-81 is a potent antagonist of human and rodent smoothened (Smo) receptors, with an IC50 value of 41 nM in the Shh-light2 cells, exerting potent hedgehog (Hh) signaling pathway inhibiting activity.

Storage Conditions

3 years -20°C powder

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