MRT-81
Product Specifications
CAS Number
1263132-08-6
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
COC1=C (OC) C (=CC (=C1) C (=O) NC (=S) NC2=CC=C (C) C (=C2) NC (=O) C3=CC=C (C=C3) C4=CC=CC=C4) OC
Molecular Formula
C31H29N3O5S
Additionnal Information
MRT-81 is a potent antagonist of human and rodent smoothened (Smo) receptors, with an IC50 value of 41 nM in the Shh-light2 cells, exerting potent hedgehog (Hh) signaling pathway inhibiting activity.
Storage Conditions
3 years -20°C powder
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