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S18-000003

Product Specifications

CAS Number

2068119-11-7

Target

ROR

Applications

Metabolism

Smiles

CC[S] (=O) (=O) C1=CC=C (CC (=O) NC2=CC (=C (C=C2) C (C) (C) C (=O) NC3=C (F) C=C (F) C=C3) F) C=C1

Molecular Formula

C26H25F3N2O4S

Additionnal Information

S18-000003, a potent, selective and orally active inhibitor of retinoic acid receptor-related orphan receptor-gamma-t (RORγt), with an IC50 of <30 μM towards human RORγt in competitive binding assays.

Storage Conditions

3 years -20°C powder

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