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Parsaclisib (INCB050465)

Product Specifications

CAS Number

1426698-88-5

Synonyms

INCB-50465, IBI376

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

CCOC1=C (C2CNC (=O) C2) C (=C (Cl) C=C1C (C) [N]3N=C (C) C4=C (N) N=CN=C34) F

Molecular Formula

C20H22ClFN6O2

Additionnal Information

Parsaclisib (INCB050465, INCB-50465, IBI376) is a potent and highly selective PI3Kδ (PI3K delta) inhibitor with an IC50 of 1 nM at 1 mM ATP in biochemical assay and approximately 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.

Storage Conditions

3 years -20°C powder

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