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PF-06446846 hydrochloride

Product Specifications

CAS Number

1632250-50-0

Synonyms

PF846

Target

PCSK9

Applications

Metabolism

Smiles

Cl.ClC1=C (N=CC=C1) N (C2CCCNC2) C (=O) C3=CC=C (C=C3) [N]4N=NC5=C4N=CC=C5

Molecular Formula

C22H21Cl2N7O

Additionnal Information

PF-06446846 (PF846) Hydrochloride is an orally bioavailable and specific inhibitor of PCSK9 with an IC50 of 0.3 μM in Huh7 cells.

Storage Conditions

3 years -20°C powder

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