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LQZ-7I

Product Specifications

CAS Number

195822-23-2

Target

Survivin

Applications

Apoptosis

Smiles

FC1=CC=C (NC2=NC3=CC=CC=C3N=C2NC4=CC=C (F) C=C4) C=C1

Molecular Formula

C20H14F2N4

Additionnal Information

LQZ-7I is a novel selectively inhibitor of survivin dimerization with IC50s of 4.8 μM and 3.1 μM in prostate cancer cell lines PC-3 and C4-2, respectively. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.

Storage Conditions

3 years -20°C powder

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