I-191
Product Specifications
CAS Number
1690172-25-8
Target
PAR
Applications
GPCR & G Protein
Smiles
CC (C) (C) C1=CC (=N[N]2C=C (N=C12) C (=O) N3CCNC (=O) C3 (C) C) C4=CC=C (F) C=C4
Molecular Formula
C23H26FN5O2
Additionnal Information
I-191 is a potent PAR2 antagonist that inhibits multiple PAR2-induced signaling pathways and functional responses. I-191 also inhibits ERK1/2 phosphorylation, RhoA activation, and inhibition of forskolin-stimulated cAMP accumulation induced by micromolar concentrations of biased ligand GB88.
Storage Conditions
3 years -20°C powder
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