R59949
Product Specifications
CAS Number
120166-69-0
Target
Others
Applications
Others
Smiles
FC1=CC=C (C=C1) C (=C2CCN (CCN3C (=S) NC4=CC=CC=C4C3=O) CC2) C5=CC=C (F) C=C5
Molecular Formula
C28H25F2N3OS
Additionnal Information
R59949, a diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM, inhibits inducible nitric oxide production through decreasing transplasmalemmal L-arginine uptake in vascular smooth muscle cells. R59949 strongly inhibits type I DGK a and γ, and moderately attenuates type II DGK θ and κ.
Storage Conditions
3 years -20°C powder
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