NiCur
Product Specifications
CAS Number
63476-70-0
Target
Histone Acetyltransferase
Applications
Epigenetics
Smiles
O=C\1/C (CCCC1=C\C2=CC (=CC=C2) C#N) =C/C3=CC (=CC=C3) C#N
Molecular Formula
C22H16N2O
Additionnal Information
NiCur is a small molecule which blocks CREB-binding protein (CBP) histone acetyltransferase (HAT) activity and downregulates p53 activation upon genotoxic stress and diminishs the recruitment of p53 as well as RNA Polymerase II and levels of acetylation on histone H3 on CDKN1A promoter.
Storage Conditions
3 years -20°C powder
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