Tolebrutinib
Product Specifications
CAS Number
1971920-73-6
Synonyms
SAR442168, PRN2246
Target
BTK
Applications
Protein Tyrosine Kinase
Smiles
NC1=NC=CC2=C1N (C (=O) N2C3CCCN (C3) C (=O) C=C) C4=CC=C (OC5=CC=CC=C5) C=C4
Molecular Formula
C26H25N5O3
Additionnal Information
Tolebrutinib is an oral, CNS-penetrant, irreversible inhibitor of Bruton's tyrosine kinase (BTK) with IC50s of 0.4 nM and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively.
Storage Conditions
3 years -20°C powder
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