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RN-1747

Product Specifications

CAS Number

1024448-59-6

Target

TRP Channel

Applications

Neuronal Signaling

Smiles

[O-][N+] (=O) C1=C (C=CC (=C1) Cl) [S] (=O) (=O) N2CCN (CC2) CC3=CC=CC=C3

Molecular Formula

C17H18ClN3O4S

Additionnal Information

RN-1747 is a selective TRPV4 agonist with EC50s of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 also antagonizes TRPM8 with IC50 of 4 μM.

Storage Conditions

3 years -20°C powder

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