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Cynomolgus DR3 / TNFRSF25 Protein, His Tag (SPR verified)

Cynomolgus DR3 Protein, His Tag (DR3-C52H3) is expressed from human 293 cells (HEK293) . It contains AA Gln 20 - Gly 203 (Accession # G7NTB5-1) .

Product Specifications

Background

Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.7 kDa. The protein migrates as 33-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

G7NTB5-1

Expression Region

Gln 20 - Gly 203

Host

HEK293

Target

DR3

Conjugation

Unconjugated

Tag

C-10xHis

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

21.7 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

1mg*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/DR3-C52H3.pdf

Species

Cynomolgus

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