Linderalactone
Product Specifications
CAS Number
728-61-0
Target
Bcl-2
Applications
Apoptosis
Smiles
CC/1=C\CCC2=CC (OC2=O) C3=C (C1) OC=C3C
Molecular Formula
C15H16O3
Additionnal Information
Linderalactone inhibits human lung cancer growth by modulating the expression of apoptosis-related proteins (Bax and Bcl-2) with an IC50 of 15 μM in A-549 cells. Linderalactone induces G2/M cell cycle arrest and could also suppress the JAK/STAT signalling pathway. Linderalactone can be isolated from Radix linderae.
Storage Conditions
3 years -20°C powder
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