Serclutamab talirine
Product Specifications
CAS Number
2140174-56-5
Synonyms
ABBV-321, Anti-Egfr/pbd antibody-drug conjugate ABBV-321
Target
EGFR
Applications
Protein Tyrosine Kinase
Additionnal Information
Serclutamab Talirine (ABBV-321), is an antibody-drug conjugate (ADC) composed of an humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclutamab Talirine has the potential for use in advanced solid tumors associated with overexpression of the epidermal growth factor receptor (EGFR) or its ligands.
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
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