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Serclutamab talirine

Product Specifications

CAS Number

2140174-56-5

Synonyms

ABBV-321, Anti-Egfr/pbd antibody-drug conjugate ABBV-321

Target

EGFR

Applications

Protein Tyrosine Kinase

Additionnal Information

Serclutamab Talirine (ABBV-321), is an antibody-drug conjugate (ADC) composed of an humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclutamab Talirine has the potential for use in advanced solid tumors associated with overexpression of the epidermal growth factor receptor (EGFR) or its ligands.

Storage Conditions

Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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